This list has been reviewed in December 2005 by Dr Mary Reilly from the National Hospital for Neurology, London, and Dr David Hilton-Jones, from the Radcliffe Infirmary, Oxford, and their advise is as follows:

Many drugs can cause peripheral neuropathy. There is NO evidence that this means that these drugs can worsen an existing neuropathy, such as CMT.   Bearing that in mind, however, do remember that there are alternatives for all of these drugs.

The only drug on this list that has been proven to be toxic to someone with CMT is Vincristine – an anti-cancer drug.

In particular, the benefits of Statins far outweighs the potential harm – see more detail on this in the Drug section of the FAQ’s.

With any drug, whether it is on this list or not, it is always wise to discuss prescribed medications with your medical professions, including any potential side-effects, whilst keeping the diagnosis of CMT in the patient in mind.

Alcoholism (excessive alcohol may worse neuropathy symptoms)
Anabuse
Disulfram

AIDs
Nucleosides

Antiobiotics
Chloramphenicol
Penicillin (large IV doses)
Metronidazole

Anti-Arrhythmic
Procainamide
Propafenone

Anti-depressants / Pyschiatric Disorders
Zimeldine
Lithium
Zoloft (Sertraline)
Misomidazole

Anti-Epileptic
Phenytoin
Dilantin

Cardiac conditions
Amiodarone (Cordarone)
Perhixiline (Pexid)

Chemotherapy Agents
Adriamycin
Bortezomib (Velcade)
Chloramphenicol
Cisplatinum (all Platinum analogs)
Doxorubicin
Etoposide (VP-16)
Infosfamide
Nitrous Oxide (N20)
Interferon-a
Misomidazole – adjunct to radiation therapy (Metronidazole)
Suramin
Taxol (Paclitaxel, docetaxel)
Thalidomide
Vincristine (all Vinca alkaloids)

Anaesthetic
Nitrous Oxide – chronic repeated inhalation

Dietary Supplements (vitamins and herbal remedies)
Mega doses of Vitamin A, D & B6)
Valarian Root

Gout
Colchicine

Hepatitis C
Interferon-a

Hypertension
Hydralazine (apresoline)

Infections (vaginal)
Metronidazole (Flagyl)
Glutethimide (Doriden)

Leprosy
Dapsone

Cholesterol Lowering Agent
Statins (Lovastatin, Pravastatin, Simvastatin)

Pain
Dilantin

Respiratory Disorders / Tuberculosis
Almitrine
Ethambutol

Rheumatoid Arthritis
Gold (Aurothioglucose)
Penicillamine
Leflunomide (arava)

Sedative / Insomnia
Glutethimide

Urinary Tract Infections
Nitrofurantoin (Furadantin, Macrodantin, Macrobid)

Compiled by the Neuromuscular Disease Centre, Washington University, St Louis, MO.

This article may be of interest, regarding this subject too - also taken from the HNF Website:

 how_risky_are_your_medications 06/12/2007,04:13 41.00 Kb 

 

 

Reprinted with kind permission of the Hereditary Neuropathy Foundation.

Last Updated ( Tuesday, 30 June 2009 )